Article
Association of tumor necrosis factor receptor type 2 +587 gene polymorphism with severe chronic periodontitis.
Journal of clinical periodontology - 1 Jun 2004
Shimada Yasuko, Tai Hideaki, Endo Motohiro, Kobayashi Tetsuo, Akazawa Kohei, Yamazaki Kazuhisa
Abstract excerpt
BACKGROUND: Genetic polymorphisms for cytokines and their receptors have been proposed as potential markers for periodontal disease. Tumor necrosis factor receptor 2 (TNFR2) is one of the cell surface receptors for TNF-alpha. Recent studies have suggested that TNFR2 gene polymorphism is involved in autoimmune and other diseases. OBJECTIVES: The aim of the present study is to evaluate whether TNFR2(+587T/G) gene...
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