Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression analysis suggests that 1,25-dihydroxyvitamin D<sub>3</sub>reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis

18 May 2004

Abstract excerpt

Multiple sclerosis (MS) is a debilitating autoimmune disease of the central nervous system (CNS) that develops in genetically susceptible individuals who are exposed to undefined environmental risk factors. Epidemiological, genetic, and biological evidence suggests that insufficient vitamin D may be an MS risk factor. However, little is known about how vitamin D might be protective in MS. We hypothesized that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Vitamin D Research Studies
Share to Whipple's Disease and Interleukins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15138306
DOI: 10.1152/physiolgenomics.00003.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression analysis suggests that 1,25-dihydroxyvitamin D<sub>3</sub>reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosisPMID 15138306Read ↗

Linking Mechanisms of Vitamin D Signaling with Multiple SclerosisSemantic proximity Read ↗

Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitisSemantic proximity Read ↗

Vitamins D3 and D2 have marked but different global effects on gene expression in a rat oligodendrocyte precursor cell lineSemantic proximity Read ↗

Characterization of the multiple sclerosis traits: Nuclear receptors (NR) impaired apoptosis pathway and the role of 1-alpha 25-dihydroxyvitamin D3Semantic proximity Read ↗

Additional Clues for a Protective Role of Vitamin D in Neurodegenerative Diseases: 1,25-Dihydroxyvitamin D3 Triggers an Anti-Inflammatory Response in Brain PericytesSemantic proximity Read ↗

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitisSemantic proximity Read ↗

MiRNA-29b modulates neuroinflammation by targeting T-bet in Experimental Autoimmune Encephalomyelitis mice treated with vitamins A and DSemantic proximity Read ↗

Vitamin D and its immunoregulatory role in multiple sclerosis.Semantic proximity Read ↗

The Ifng Gene Is Essential for Vdr Gene Expression and Vitamin D3-Mediated Reduction of the Pathogenic T Cell Burden in the Central Nervous System in Experimental Autoimmune Encephalomyelitis, a Multiple Sclerosis ModelSemantic proximity Read ↗

Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environmentSemantic proximity Read ↗

Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by LovastatinSemantic proximity Read ↗

Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.