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Article

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.

Journal of cell science - 1 Jun 2004

Gutierrez Maximiliano G, Munafó Daniela B, Berón Walter, Colombo María I

Abstract excerpt

Autophagy is a normal degradative pathway that involves the sequestration of cytoplasmic components and organelles in a vacuole called an autophagosome that finally fuses with the lysosome. Rab7 is a member of the Rab family involved in transport to late endosomes and in the biogenesis of the perinuclear lysosome compartment. To assess the role of Rab7 in autophagy we stably transfected CHO cells with wild-type...

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Identifiers

PMID: 15138286
DOI: 10.1242/jcs.01114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.PMID 15138286Read ↗

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