Article
Mutation accumulation and the effect of copia insertions in Drosophila melanogaster.
Genetical research - 1 Feb 2004
Houle David, Nuzhdin Sergey V
Abstract excerpt
Repeated efforts to estimate the genomic deleterious mutation rate per generation (U) in Drosophila melanogaster have yielded inconsistent estimates ranging from 0.01 to nearly 1. We carried out a mutation-accumulation experiment with a cryopreserved control population in hopes of resolving some of the uncertainties raised by these estimates. Mutation accumulation (MA) was carried out by brother sister mating of...
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