Article
Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population.
European journal of human genetics : EJHG - 1 Mar 2011
Tanimura Daisuke, Shibata Rei, Izawa Hideo, Hirashiki Akihiro, Asano Hiroyuki, Murase Yosuke, Miyata Seiko, Nakatochi Masahiro, Ouchi Noriyuki, Ichihara Sahoko, Yasui Kenji, Yoshida Tsutomu, Naruse Keiko, Matsubara Tatsuaki, Yokota Mitsuhiro
Abstract excerpt
Adiponectin is an adipocyte-derived protein that is down-regulated in obesity-linked disorders. Variants of the adiponectin gene (ADIPOQ) have been shown to affect adiponectin level. We have now examined the relation of polymorphisms of ADIPOQ to adiponectin concentration and to metabolic disorders in the Kita-Nagoya Genomic Epidemiology study, a population-based study of elderly Japanese. The genomic region...
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