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Article

Maintenance of G1 checkpoint controls in telomerase-immortalized endothelial cells.

Cell cycle (Georgetown, Tex.) - 1 Jun 2004

Freedman Deborah A, Folkman Judah

Abstract excerpt

Here we report the characterization of a series of telomerase-immortalized human umbilical vein endothelial cell lines (i-HUVEC). These cells maintain endothelial characteristics such as marker expression, dependence on basic fibroblast growth factor for proliferation, and the ability to form tube structures on Matrigel. In addition, these cells do not show signs of tumorigenic transformation because their growth...

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PMID: 15118409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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