Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytochrome P-450 2D6*10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients.

Neuropsychobiology - 1 Jan 2004

Liou Ying-Jay, Wang Ying-Chieh, Bai Ya-Mei, Lin Chao-Cheng, Yu Shun-Chieh, Liao Ding-Lieh, Lin Ming-Wei, Chen Jen-Yeu, Lai I-Ching

Abstract excerpt

Typical antipsychotic treatment had been postulated to be a risk factor for the susceptibility to tardive dyskinesia (TD). The cytochrome P-450 debrisoquine/sparteine hydroxylase (CYP2D6) metabolizes a majority of antipsychotics and exhibits various phenotypes on enzymatic activities from poor metabolizers to ultrarapid metabolizers. The various phenotypes are encoded by polymorphic genetic variants on the CYP2D6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Cysteine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Dyskinesia, Drug-Induced

Share to Logistic Models

Share to Schizophrenia

Share to Statistics, Nonparametric

Share to Threonine

Source

Identifiers

PMID: 15118351
DOI: 10.1159/000077360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytochrome P-450 2D6*10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients.PMID 15118351Read ↗

Cytochrome P450 2D6 genotyping and association with tardive dyskinesia in Chinese schizophrenic patients.Semantic proximity Read ↗

Association of CYP2D6 and CYP1A2 gene polymorphism with tardive dyskinesia in Chinese schizophrenic patients.Semantic proximity Read ↗

Tardive dyskinesia and debrisoquine 4-hydroxylase (CYP2D6) genotype in Japanese schizophrenics.Semantic proximity Read ↗

Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia.Semantic proximity Read ↗

Genetic underpinnings of tardive dyskinesia: passing the baton to pharmacogenetics.Semantic proximity Read ↗

Genetics of tardive dyskinesia.Semantic proximity Read ↗

CYP2D6 polymorphism and tardive dyskinesia in schizophrenic patients.Semantic proximity Read ↗

Association between CYP2D6 genotype and tardive dyskinesia in Korean schizophrenics.Semantic proximity Read ↗

Genetic association analysis of functional polymorphisms in the cytochrome P450 1A2 (CYP1A2) gene with tardive dyskinesia in Japanese patients with schizophrenia.Semantic proximity Read ↗

CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis.Semantic proximity Read ↗

Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients.Semantic proximity Read ↗

Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.