Article
Angiotensin converting enzyme genotype and strength in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine - 15 Aug 2004
Hopkinson Nicholas S, Nickol Annabel H, Payne John, Hawe Emma, Man William D-C, Moxham John, Montgomery Hugh, Polkey Michael I
Abstract excerpt
Quadriceps muscle weakness is an important contributor to exercise limitation in patients with chronic obstructive pulmonary disease. The deletion allele of the angiotensin converting enzyme gene polymorphism has previously been associated with a greater response to strength training in healthy subjects and might, therefore, protect against detraining in these patients. In 103 stable outpatients (mean [SD] FEV(1)...
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