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Article

Prediction of virological response to lopinavir/ritonavir using the genotypic inhibitory quotient.

AIDS research and human retroviruses - 1 Mar 2004

González de Requena Daniel, Gallego Oscar, Valer Luisa, Jiménez-Nácher Inmaculada, Soriano Vincent

Abstract excerpt

The predictive value of virological response to lopinavir (LPV)/ritonavir (r) was assessed in 126 HIV-infected patients who failed antiretroviral therapy and had begun a rescue intervention based on LPV/r. At 3 months, subjects with < or =6 protease (PRO) resistance mutations showed a higher rate of virological response (HIV-RNA drop > 1 log or to <50 copies/ml) than patients with >6 PRO resistance mutations (77%...

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Source

Identifiers

PMID: 15117450
DOI: 10.1089/088922204322996509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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