Article
Graphical modeling of the joint distribution of alleles at associated loci.
American journal of human genetics - 1 Jun 2004
Thomas Alun, Camp Nicola J
Abstract excerpt
Pairwise linkage disequilibrium, haplotype blocks, and recombination hotspots provide only a partial description of the patterns of dependences and independences between the allelic states at proximal loci. On the gross scale, where recombination and spatial relationships dominate, the associations can be reasonably described in these terms. However, on the fine scale of current high-density maps, the mutation...
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