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Article

Blocking of human immunodeficiency virus type-1 virion autolysis by autologous p2(gag) peptide.

Journal of biochemistry - 1 Mar 2004

Misumi Shogo, Morikawa Yukimi, Tomonaga Mitsunori, Ohkuma Kouichi, Takamune Nobutoki, Shoji Shozo

Abstract excerpt

Our previous study suggested that the p2(gag) peptide, AEAMSQVTNTATIM, inhibits human immunodeficiency virus type 1 (HIV-1) protease (PR) activity in vitro. In this study, Ala substitutions (Met4Ala and Thr8Ala) and deletion of amino acid Asn9 within the nona p2(gag) peptide (AEAMSQVTN) were found to decrease the inhibitory effect on HIV-1 PR activity. Furthermore, treatment of PMA-activated latently infected T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15113844
DOI: 10.1093/jb/mvh052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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