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Glucose starvation results in UDP-glucose deficiency and inactivation of glycogen synthase.

Archives of biochemistry and biophysics - 15 May 2004

Higuita Juan Carlos, Thelestam Monica, Katz Abram

Abstract excerpt

The effects of glucose starvation on glycogen synthase (GS) activity and protein expression were investigated. Fibroblasts were cultured in medium supplemented with either glucose or pyruvate. Pyruvate-cultured cells exhibited UDP-glucose contents that amounted to approximately 10% of those in cells cultured with glucose. GS activity, protein and mRNA amounts in pyruvate-cultured cells were decreased to...

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PMID: 15111133
DOI: 10.1016/j.abb.2004.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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