Article
Mitochondrial respiratory mutants in yeast inhibit glycogen accumulation by blocking activation of glycogen synthase.
The Journal of biological chemistry - 20 Nov 1998
Yang R, Chun K T, Wek R C
Abstract excerpt
Control of glycogen synthase activity by protein phosphorylation is important for regulating the synthesis of glycogen. In this report, we describe a regulatory linkage between the ability of yeast cells to respire and activation of glycogen synthase. Strains containing respiration-deficient muta...
Topics
- Adenosine Triphosphate
- Amino Acid Sequence
- Cyclic AMP-Dependent Protein Kinases
- Enzyme Activation
- Fungal Proteins
- Glucose
- Glucose-6-Phosphate
- Glycogen
- Glycogen Synthase
- Isoenzymes
- Mitochondria
- Molecular Sequence Data
- Mutation
- Oxygen Consumption
- Phosphorylation
- Saccharomyces cerevisiae
- Serine
- Threonine