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Article

Novel P143L polymorphism of the LCAT gene is associated with dyslipidemia in Chinese patients who have coronary atherosclerotic heart disease.

Biochemical and biophysical research communications - 21 May 2004

Zhang Kelan, Zhang Sizhong, Zheng Keqin, Hou Yiping, Liao Linchuan, He Yong, Zhang Li, Nebert Daniel W, Shi Jiajun, Su Zhiguang, Xiao Cuiying

Abstract excerpt

Coronary atherosclerotic heart disease (CAD) is a multifactorial disorder resulting from numerous gene-gene and gene-environment interactions. Lecithin:cholesterol acyltransferase (LCAT), a key enzyme in reverse cholesterol transport and the metabolism of high-density lipoprotein (HDL), is thought to be a candidate gene related to dyslipidemia and CAD. Variations in the LCAT gene were investigated in 190 CAD...

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Source

Identifiers

PMID: 15110745
DOI: 10.1016/j.bbrc.2004.03.177

Genes

CAD
LCAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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