Article
Distinct cellular origins of primary effusion lymphoma with and without EBV infection.
Leukemia research - 1 Apr 2004
Hamoudi Rifat, Diss Tim C, Oksenhendler Eric, Pan Langxing, Carbone Antonino, Ascoli Valeria, Boshoff Chris, Isaacson Peter, Du Ming-Qing
Abstract excerpt
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with three distinct lymphoproliferative disorders: primary effusion lymphoma (PEL), multicentric Castleman's disease (MCD) and germinotropic lymphoproliferative disorder (GLD). KSHV positive lymphocytes in GLD and in most cases of PEL are co-infected by Epstein-Barr virus (EBV) and these viral double positive cells harbour mutated rearranged...
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