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Article

Genetic characterization of HHV-8/KSHV-positive primary effusion lymphoma reveals frequent mutations of BCL6: implications for disease pathogenesis and histogenesis.

Genes, chromosomes & cancer - 1 Jan 1999

Gaidano G, Capello D, Cilia A M, Gloghini A, Perin T, Quattrone S, Migliazza A, Lo Coco F, Saglio G, Ascoli V, Carbone A

Abstract excerpt

Human herpesvirus-8/Kaposi sarcoma-associated herpesvirus-positive primary effusion lymphoma (PEL) is a recently identified B-cell non-Hodgkin lymphoma category characterized by liquid growth in the serous body cavities. Apart from viral infection, no genetic alteration is known to be associated...

Topics

5' Untranslated Regions
DNA Mutational Analysis
DNA-Binding Proteins
Genetic Predisposition to Disease
Herpesviridae Infections
Herpesvirus 8, Human
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-bcl-6

Transcription Factors

Tumor Cells, Cultured

Source

Identifiers

PMID: 9892104
DOI: 10.1002/(sici)1098-2264(199901)24:1<16::aid-gcc3>3.0.co;2-f

Genes

BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9892104-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genetic characterization of HHV-8/KSHV-positive primary effusion lymphoma reveals frequent mutations of BCL6: implications for disease pathogenesis and histogenesis.PMID 9892104Read ↗

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