Article
Genetic characterization of HHV-8/KSHV-positive primary effusion lymphoma reveals frequent mutations of BCL6: implications for disease pathogenesis and histogenesis.
Genes, chromosomes & cancer - 1 Jan 1999
Gaidano G, Capello D, Cilia A M, Gloghini A, Perin T, Quattrone S, Migliazza A, Lo Coco F, Saglio G, Ascoli V, Carbone A
Abstract excerpt
Human herpesvirus-8/Kaposi sarcoma-associated herpesvirus-positive primary effusion lymphoma (PEL) is a recently identified B-cell non-Hodgkin lymphoma category characterized by liquid growth in the serous body cavities. Apart from viral infection, no genetic alteration is known to be associated with PEL and no recurrent cytogenetic abnormality has been identified in these lymphomas. Yet the consistent...
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