Article
A genomewide scan identifies novel early-onset primary open-angle glaucoma loci on 9q22 and 20p12.
American journal of human genetics - 1 Jun 2004
Wiggs J L, Lynch S, Ynagi G, Maselli M, Auguste J, Del Bono E A, Olson L M, Haines J L
Abstract excerpt
Glaucoma is a leading cause of blindness worldwide. The disease is characterized by a degeneration of the optic nerve, which is usually associated with elevated intraocular pressure. The common form of adult-onset primary open-angle glaucoma is inherited as a complex trait, whereas the rarer early-onset juvenile open-angle glaucoma (JOAG) exhibits autosomal dominant inheritance. Of all cases of JOAG,...
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