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Article

The genetics of open-angle glaucoma: the story of GLC1A and myocilin.

Eye (London, England) - 1 Jun 2000

Alward W L

Abstract excerpt

A linkage analysis study was performed on a single large family with juvenile-onset primary open-angle glaucoma (POAG). This led to the recognition that there was a region of chromosome 1q that harboured a gene for juvenile-onset POAG. This chromosomal site was called GLC1A. It was discovered that a gene that produces the protein myocilin resides within this interval and that mutations in myocilin caused most...

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Identifiers

PMID: 11026970
DOI: 10.1038/eye.2000.127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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