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Article

Mechanisms of azole resistance in petite mutants of Candida glabrata.

Antimicrobial agents and chemotherapy - 1 May 2004

Brun Sophie, Bergès Thierry, Poupard Pascal, Vauzelle-Moreau Carole, Renier Gilles, Chabasse Dominique, Bouchara Jean-Philippe

Abstract excerpt

We previously showed that resistant colonies of Candida glabrata inside the azole inhibition zones had respiratory deficiency due to mutations in mitochondrial DNA. Here, we analyzed the mechanisms of azole resistance in petite mutants of C. glabrata obtained by exposure to fluconazole or induced by ethidium bromide. The respiratory deficiency of these mutants was confirmed by oxygraphy and flow cytometric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15105136
DOI: 10.1128/AAC.48.5.1788-1796.2004
PMCID: PMC400549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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