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Article

Prevention of Pneumococcal Disease in Mice Immunized with Conserved Surface-Accessible Proteins

21 Apr 2004

Abstract excerpt

The development of a vaccine against Streptococcus pneumoniae has been complicated by the existence of at least 90 antigenically distinct capsular serotypes. Common protein-based vaccines could represent the best strategy to prevent pneumococcal infections, regardless of serotype. In the present study, the immunoscreening of an S. pneumoniae genomic library allowed the identification of a novel immune protein...

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Identifiers

PMID: 15102774
DOI: 10.1128/iai.72.5.2659-2670.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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