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Article

Increased formation of reactive oxygen species, but no changes in glutathione peroxidase activity, in striata of mice transgenic for the Huntington's disease mutation.

Neurochemical research - 1 Apr 2004

Pérez-Severiano Francisca, Santamaría Abel, Pedraza-Chaverri José, Medina-Campos Omar N, Ríos Camilo, Segovia José

Abstract excerpt

The formation of reactive oxygen species (ROS) and the activities of the antioxidant enzymes glutathione peroxidase (GPx) and catalase (CAT) were measured as a function of age in the striatum of mice transgenic for the Huntington's disease (HD) mutation. Striata from R6/1 transgenic male mice wer...

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Identifiers

PMID: 15098934
DOI: 10.1023/b:nere.0000018843.83770.4b

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15098934-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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