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Article

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum.

The Journal of biological chemistry - 2 Jul 2004

Miranda Elena, Römisch Karin, Lomas David A

Abstract excerpt

The dementia familial encephalopathy with neuroserpin inclusion bodies (FENIB) is caused by the accumulation of mutant neuroserpin within neurons (Davis, R. L., Shrimpton, A. E., Holohan, P. D., Bradshaw, C., Feiglin, D., Sonderegger, P., Kinter, J., Becker, L. M., Lacbawan, F., Krasnewich, D., Muenke, M., Lawrence, D. A., Yerby, M. S., Shaw, C.-M., Gooptu, B., Elliott, P. R., Finch, J. T., Carrell, R. W., and...

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Identifiers

PMID: 15090543
DOI: 10.1074/jbc.M313166200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum.PMID 15090543Read ↗

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Lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies.Semantic proximity Read ↗

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