Article
Kinetic analysis of beta-amyloid fibril elongation.
Analytical biochemistry - 1 May 2004
Cannon Michelle J, Williams Angela D, Wetzel Ronald, Myszka David G
Abstract excerpt
We used surface plasmon resonance biosensors to evaluate the kinetics associated with the initial events of beta-amyloid (Abeta) fibril elongation. Fibrils were immobilized on the sensor chip surface and extended by exposure to soluble Abeta(1-40) peptide. The fibril surfaces bound Congo red, a m...
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