Article
Parvalbumin deficiency affects network properties resulting in increased susceptibility to epileptic seizures.
Molecular and cellular neurosciences - 1 Apr 2004
Schwaller B, Tetko I V, Tandon P, Silveira D C, Vreugdenhil M, Henzi T, Potier M-C, Celio M R, Villa A E P
Abstract excerpt
Networks of GABAergic interneurons are of utmost importance in generating and promoting synchronous activity and are involved in producing coherent oscillations. These neurons are characterized by their fast-spiking rate and by the expression of the Ca(2+)-binding protein parvalbumin (PV). Altera...
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