Article
A novel motif in geminivirus replication proteins interacts with the plant retinoblastoma-related protein.
Journal of virology - 1 May 2004
Arguello-Astorga Gerardo, Lopez-Ochoa Luisa, Kong Ling-Jie, Orozco Beverly M, Settlage Sharon B, Hanley-Bowdoin Linda
Abstract excerpt
The geminivirus replication factor AL1 interacts with the plant retinoblastoma-related protein (pRBR) to modulate host gene expression. The AL1 protein of tomato golden mosaic virus (TGMV) binds to pRBR through an 80-amino-acid region that contains two highly predicted alpha-helices designated 3 and 4. Earlier studies suggested that the helix 4 motif, whose amino acid sequence is strongly conserved across...
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