Article
cis- and trans-acting functions of brome mosaic virus protein 1a in genomic RNA1 replication.
Journal of virology - 1 Mar 2008
Yi Guanghui, Kao Cheng
Abstract excerpt
RNA viruses employ a combination of mechanisms to regulate their gene expression and replication. Brome mosaic virus (BMV) is a tripartite positive-strand RNA virus used to study the requirements for virus infection. BMV genomic RNA1 encodes protein 1a, which contains a methyltransferase (MT) domain and a helicase domain that are required for replication. 1a forms a complex with the 2a RNA-dependent RNA...
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