Article
The multifunctional character of a geminivirus replication protein is reflected by its complex oligomerization properties.
The Journal of biological chemistry - 3 Mar 2000
Orozco B M, Kong L J, Batts L A, Elledge S, Hanley-Bowdoin L
Abstract excerpt
Tomato golden mosaic virus (TGMV), a member of the geminivirus family, encodes one essential replication protein, AL1, and recruits the rest of the DNA replication apparatus from its plant host. TGMV AL1 is an oligomeric protein that binds double-stranded DNA and catalyzes cleavage and ligation of single-stranded DNA. The oligomerization domain, which is required for DNA binding, maps to a region that displays...
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