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Article

Evolutionary and functional relationships within the DJ1 superfamily

19 Feb 2004

Abstract excerpt

BACKGROUND: Inferences about protein function are often made based on sequence homology to other gene products of known activities. This approach is valuable for small families of conserved proteins but can be difficult to apply to large superfamilies of proteins with diverse function. In this study we looked at sequence homology between members of the DJ-1/ThiJ/PfpI superfamily, which includes a human protein of...

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PMID: 15070401
DOI: 10.1186/1471-2148-4-6

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