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Article

Sarcoendoplasmic reticulum Ca(2+) ATPase type 2 downregulated in human oral squamous cell carcinoma.

International journal of cancer - 10 Jun 2004

Endo Yosuke, Uzawa Katsuhiro, Mochida Yoshiyuki, Shiiba Masashi, Bukawa Hiroki, Yokoe Hidetaka, Tanzawa Hideki

Abstract excerpt

Mice with a heterozygous deletion of the Atp2a2 gene (Atp2a2(+/-)) encoding SERCA2 spontaneously develop SCCs of the skin and upper digestive tract, including the oral cavity. To elucidate the contribution of ATP2A2 to human oral carcinogenesis, we analyzed genetic and epigenetic changes as well...

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Source

Identifiers

PMID: 15069686
DOI: 10.1002/ijc.20118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15069686-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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