Article
Detection of SYT-SSX mutant transcripts in formalin-fixed paraffin-embedded sarcoma tissues using one-step reverse transcriptase real-time PCR.
The Malaysian journal of pathology - 1 Apr 2016
Norlelawati A T, Mohd Danial G, Nora H, Nadia O, Zatur Rawihah K, Nor Zamzila A, Naznin M
Abstract excerpt
BACKGROUND: Synovial sarcoma (SS) is a rare cancer and accounts for 5-10% of adult soft tissue sarcomas. Making an accurate diagnosis is difficult due to the overlapping histological features of SS with other types of sarcomas and the non-specific immunohistochemistry profile findings. Molecular testing is thus considered necessary to confirm the diagnosis since more than 90% of SS cases carry the transcript of...
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