Article
Molecular Characterization of Synovial Sarcoma in Children and Adolescents: Evidence of Akt Activation
1 Jul 2008
Abstract excerpt
Synovial sarcoma (SS) is the most frequent nonrhabdomyosarcomatous soft tissue sarcoma encountered in adolescents and young adults, and despite advances in the treatment of local disease, metastases remain the main cause of death. The aim of this study was to characterize a single-center series of pediatric SS molecularly to seek any biomarkers or pathways that might make suitable targets for new agents....
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