Article
Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22.
American journal of human genetics - 1 May 2004
Brzustowicz Linda M, Simone Jaime, Mohseni Paria, Hayter Jared E, Hodgkinson Kathleen A, Chow Eva W C, Bassett Anne S
Abstract excerpt
Previously, we have reported linkage of markers from chromosome 1q22 to schizophrenia, a finding supported by several independent studies. We have now examined the region of strongest linkage for evidence of linkage disequilibrium (LD) in a sample of 24 Canadian familial-schizophrenia pedigrees. Analysis of 14 microsatellites and 15 single-nucleotide polymorphisms (SNPs) from the 5.4-Mb region between D1S1653 and...
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