Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of hepatocyte growth factor promoter polymorphism with severity of interstitial lung disease in Japanese patients with systemic sclerosis.

Arthritis and rheumatism - 1 Aug 2011

Hoshino Kana, Satoh Takashi, Kawaguchi Yasushi, Kuwana Masataka

Abstract excerpt

OBJECTIVE: To examine associations of single-nucleotide polymorphisms (SNPs) within genes for hepatocyte growth factor (HGF) and its receptor c-met with disease susceptibility and organ involvement in Japanese patients with systemic sclerosis (SSc). METHODS: Four SNPs (HGF -1652 C/T, +44222 C/T, and +63555 G/T, and c-met -980 T/A) were analyzed in 159 SSc patients and 103 healthy control subjects with the use of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Hepatocyte Growth Factor

Share to Lung Diseases, Interstitial

Share to Promoter Regions, Genetic

Share to Scleroderma, Systemic

Share to Severity of Illness Index

Source

Identifiers

PMID: 21520010
DOI: 10.1002/art.30415

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Association of hepatocyte growth factor promoter polymorphism with severity of interstitial lung disease in Japanese patients with systemic sclerosis.PMID 21520010Read ↗

Identification of 21 single nucleotide polymorphisms in human hepatocyte growth factor gene and association with blood pressure and carotid atherosclerosis in the Japanese population.Semantic proximity Read ↗

Genetic polymorphisms in the surfactant proteins in systemic sclerosis in Japanese: T/T genotype at 1580 C/T (Thr131Ile) in the SP-B gene reduces the risk of interstitial lung disease.Semantic proximity Read ↗

Association study of a polymorphism of the CTGF gene and susceptibility to systemic sclerosis in the Japanese population.Semantic proximity Read ↗

Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma.Semantic proximity Read ↗

Transforming growth factor beta1 gene polymorphism in patients with systemic sclerosis.Semantic proximity Read ↗

Transcriptional regulation of the hepatocyte growth factor (HGF) gene by the Sp family of transcription factors.Semantic proximity Read ↗

The polymorphism of transforming growth factor-beta1 gene in Japanese patients with systemic sclerosis.Semantic proximity Read ↗

Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.