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Article

Amplification of the cyclin D1 gene is associated with tumour subsite, DNA non-diploidy and high S-phase fraction in squamous cell carcinoma of the head and neck.

Oral oncology - 1 Jul 2004

Niméus Emma, Baldetorp Bo, Bendahl Pär-Ola, Rennstam Karin, Wennerberg Johan, Akervall Jan, Fernö Mårten

Abstract excerpt

Amplification of CCND1 (cyclin D1 gene) in squamous cell carcinoma of the head and neck (SCCHN) is correlated to poor prognosis. The purpose of this study was to investigate whether CCND1 amplification is related to different subsites and also to DNA ploidy status and S-phase fraction (SPF). Biop...

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Source

Identifiers

PMID: 15063391
DOI: 10.1016/j.oraloncology.2003.12.014

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15063391-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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