Article
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
European journal of endocrinology - 1 Apr 2001
Mulatero P, Glorioso N, Fallo F, Soro A, Morra di Cella S, Carra R, Filigheddu F, Veglio F
Abstract excerpt
OBJECTIVE: 11beta-Hydroxylase and aldosterone synthase are two highly homologous genes involved in different forms of human hypertension and in different animal models of hypertension. It has been shown that the conservative substitution D147E in the human CYP11B2 gene results in an increased pro...
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