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Article

Disorders of steroid 11 beta-hydroxylase isozymes.

Endocrine reviews - 1 Aug 1994

White P C, Curnow K M, Pascoe L

Abstract excerpt

The most active corticosteroids are 11 beta-hydroxylated. Humans have two isozymes with 11 beta-hydroxylase activity that are respectively required for cortisol and aldosterone synthesis. CYP11B1 (11 beta-hydroxylase) is expressed at high levels and is regulated by ACTH, whereas CYP11B2 (aldosterone synthase) is normally expressed at low levels and is regulated by angiotensin II. In addition to 11...

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Source

Identifiers

PMID: 7988480
DOI: 10.1210/edrv-15-4-421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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