Article
[Expression and clinical significance of c-kit oncogene in gastrointestinal stromal tumors].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Apr 2002
Liu Xiaohong, Ma Dalie, Wu Lili, Bai Chenguang, Hu Hongjie
Abstract excerpt
OBJECTIVE: To investigate the clinicopathological and prognostic significance of the c-kit protein in gastrointestinal stromal tumor (GIST). METHODS: Paraffin embedded materials from 53 benign GISTs, 13 potentially malignant and 55 malignant cases were analysed for c-kit expression by immunohistochemical method, while using leiomyomas and schwannomas as controls. Positive signals were shown in cytoplasma and cell...
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