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Repression of the <i>Staphylococcus aureus</i> Accessory Gene Regulator in Serum and In Vivo

15 Feb 2002

Abstract excerpt

Subgenomic DNA microarrays were employed to evaluate the expression of the accessory gene regulator (agr locus) as well as multiple virulence-associated genes in Staphylococcus aureus. Gene expression was examined during growth of S. aureus in vitro in standard laboratory medium and rabbit serum and in vivo in subcutaneous chambers implanted in either nonimmune rabbits or rabbits immunized with staphylococcal...

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PMID: 11807070
DOI: 10.1128/jb.184.4.1095-1101.2002

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