Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

All-trans retinoid acid increases Notch1 transcript expression in acute promyelocytic leukemia.

Advances in therapy - 1 Jan 2000

Lin Jen-Tsun, Wu Ming-Shiuan, Wang Wei-Shu, Yen Chueh-Chuan, Chiou Tzeon-Jye, Liu Jin-Hwang, Yang Mu-Hua, Chao Ta-Chon, Chou Shu-Chaou, Chen Po-Min

Abstract excerpt

The effect of all-trans retinoid acid (ATRA) on the expression of Notch1 gene by real-time reverse transcriptase polymerase chain reaction (RT-PCR) in acute promyelocytic leukemia cells (APL), NB4, and HL-60 lacking t(15;17) was studied. The cells were treated with ATRA 0.5 microM for up to 96 ho...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to HL-60 Cells
Share to Leukemia, Promyelocytic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Proteins

Share to Receptor, Notch1

Share to Receptors, Cell Surface

Share to Sensitivity and Specificity

Share to Tretinoin

Source

Identifiers

PMID: 15058751
DOI: 10.1007/BF02849800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15058751-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

All-trans retinoid acid increases Notch1 transcript expression in acute promyelocytic leukemia.PMID 15058751Read ↗

The success and the challenge of all-trans retinoic acid in the treatment of cancerSemantic proximity Read ↗

Realgar-induced apoptosis and differentiation in all-trans retinoic acid (ATRA)-sensitive NB4 and ATRA-resistant MR2 cellsSemantic proximity Read ↗

Unlocking the potential of retinoic acid in anticancer therapySemantic proximity Read ↗

Retinoic acid signaling in cancer: The parable of acute promyelocytic leukemiaSemantic proximity Read ↗

Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cellsSemantic proximity Read ↗

All-transretinoic acid in the treatment of pediatric acute promyelocytic leukemiaSemantic proximity Read ↗

Distinguishing between cancer cell differentiation and resistance induced by all-trans retinoic acid using transcriptional profiles and functional pathway analysisSemantic proximity Read ↗

Retinoic acid resistance in acute promyelocytic leukemiaSemantic proximity Read ↗

ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cellsSemantic proximity Read ↗

Interferons induce normal and aberrant retinoic-acid receptors type alpha in acute promyelocytic leukemia cells: potentiation of the induction of retinoid-dependent differentiation markers.Semantic proximity Read ↗

Comparative analysis of genes regulated by PML/RARα and PLZF/RARα in response to retinoic acid using oligonucleotide arraysSemantic proximity Read ↗

All‐<i>trans</i> retinoic acid (ATRA)‐induced <i>TFEB</i> expression is required for myeloid differentiation in acute promyelocytic leukemia (APL)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.