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Article

Molecular evolution of microcephalin, a gene determining human brain size.

Human molecular genetics - 1 Jun 2004

Wang Yin-Qiu, Su Bing

Abstract excerpt

Microcephalin gene is one of the major players in regulating human brain development. It was reported that truncated mutations in this gene can cause primary microcephaly in humans with a brain size comparable with that of early hominids. We studied the molecular evolution of microcephalin by sequencing the coding region of microcephalin gene in humans and 12 representative non-human primate species covering...

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PMID: 15056608
DOI: 10.1093/hmg/ddh127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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