Article
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2008
Barbosa Patrícia R, Stabler Sally P, Trentin Renata, Carvalho Felipe R, Luchessi André D, Hirata Rosario D C, Hirata Mario H, Allen Robert H, Guerra-Shinohara Elvira M
Abstract excerpt
BACKGROUND: Cobalamin (Cbl) and folate deficiencies and gene polymorphism of key enzymes or carriers can impair homocysteine metabolism and may change the serum values of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH). We investigated the nutritional and genetic determinants for total homocysteine (tHcy), methylmalonic acid (MMA) and SAM/SAH in healthy Brazilian childbearing-age women. METHODS: Serum...
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