Article
Postprandial variations in fibrinolytic activity in middle-aged men are modulated by plasminogen activator inhibitor I 4G-675/5G genotype but not by the fat content of a meal.
The American journal of clinical nutrition - 1 Apr 2004
Sanders Thomas A B, de Grassi Tamara, Acharya Jayshree, Miller George J, Humphries Steve E
Abstract excerpt
BACKGROUND: Decreased fibrinolytic activity is associated with an increased risk of ischemic heart disease and elevated plasma triacylglycerol concentrations. OBJECTIVE: The goal was to determine whether plasminogen activator inhibitor 1 (PAI-1) and fibrinolytic activities are influenced by 1) dietary fat intake from a test meal and 2) the PAI-1 4G allele. DESIGN: A parallel randomized controlled trial was used...
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