Article
Postprandial factor VII metabolism: the effect of the R353Q and 10 bp polymorphisms.
The British journal of nutrition - 1 May 2000
Roche H M, Black I L, Noone E, Tully A M, Whitehead A S, Gibney M J
Abstract excerpt
Elevated levels of coagulation factor VII activity (FVIIc) are associated with increased risk of CHD. FVIIc is strongly determined by two polymorphisms (R353Q and 0/10 base pairs (bp)) and plasma triacylglycerol (TAG) concentrations. The Q and 10 bp polymorphisms show strong linkage disequilibrium and have been associated with lower levels of fasting FVII, but there has been little investigation of the effect of...
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