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Article

Myeloid but not epithelial tissue factor exerts protective anti-inflammatory effects in acid aspiration-induced acute lung injury.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2017

Kral-Pointner J B, Schrottmaier W C, Horvath V, Datler H, Hell L, Ay C, Niederreiter B, Jilma B, Schmid J A, Assinger A, Mackman N, Knapp S, Schabbauer G

Abstract excerpt

Essentials Tissue factor (TF) represents a central link between hemostasis and inflammation. We studied the roles of myeloid and airway epithelial TF in acid-caused acute lung injury (ALI). TF on myeloid cells displays a non-coagulatory role regulating the inflammatory response in ALI. Airway epithelial TF contributes to hemostatic functions, but is dispensable in ALI pathogenesis. SUMMARY: Introduction Acute...

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Identifiers

PMID: 28509332
DOI: 10.1111/jth.13737
PMCID: PMC5575489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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