Article
PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiency.
Biochemical and biophysical research communications - 23 Apr 2004
Naoki Katsuhiko, Asano Koichiro, Satoh Nagato, Fukunaga Kouichi, Oguma Tsuyoshi, Shiomi Tetsuya, Suzuki Yusuke, Nakajima Takeshi, Niimi Kyoko, Shiraishi Yoshiki, Ishizaka Akitoshi, Yamaguchi Kazuhiro
Abstract excerpt
Approximately 4% of the Japanese population genetically lack plasma platelet activating factor acetylhydrolase (PAF-AH) and show a higher prevalence of thromboembolic disease, but whether they are susceptible to another PAF-related disease, asthma, remains controversial. To determine the role of plasma PAF-AH in airway physiology, we performed PAF bronchoprovocation tests in 8 plasma PAF-AH-deficient subjects and...
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