Spacrcan binding to hyaluronan and other glycosaminoglycans. Molecular and biochemical studies.

Abstract excerpt

Photoreceptors project from the outer retinal surface into a specialized glycocalyx, the interphotoreceptor matrix (IPM), which contains hyaluronan (HA) and two novel proteoglycans, Spacr and Spacrcan. This matrix must be stable enough to function in the attachment of the retina to the outer eye wall yet porous enough to allow movement of metabolites between these tissues. How this matrix is organized is not...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Extracellular Matrix Proteins