Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of CD44 interactions with hyaluronan in murine L cell fibroblasts deficient in glycosaminoglycan synthesis: a role for chondroitin sulfate.

Journal of cell science - 1 Apr 1998

Esford L E, Maiti A, Bader S A, Tufaro F, Johnson P

Abstract excerpt

CD44 is a widely expressed cell adhesion molecule that binds the extracellular matrix component, hyaluronan, in a tightly regulated manner. Previous studies have shown that the CD44-hyaluronan interaction is affected by changes in the glycosylation state of CD44. In this study, we take advantage of several well-characterized murine L cell mutants defective in heparan sulfate synthesis (gro2C cells), heparan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3 Cells
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycosylation

Share to Hyaluronan Receptors

Share to L Cells

Share to Mutation

Share to Protein Binding

Source

Identifiers

PMID: 9490645
DOI: 10.1242/jcs.111.7.1021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of CD44 interactions with hyaluronan in murine L cell fibroblasts deficient in glycosaminoglycan synthesis: a role for chondroitin sulfate.PMID 9490645Read ↗

Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding.Semantic proximity Read ↗

CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment.Semantic proximity Read ↗

Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding.Semantic proximity Read ↗

Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression.Semantic proximity Read ↗

Molecular mechanisms regulating the hyaluronan binding activity of the adhesion protein CD44.Semantic proximity Read ↗

Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates cell-cell adhesion.Semantic proximity Read ↗

Herpes simplex virus infection and propagation in a mouse L cell mutant lacking heparan sulfate proteoglycans.Semantic proximity Read ↗

CD44 in inflammation and metastasis.Semantic proximity Read ↗

Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.Semantic proximity Read ↗

Hyaluronan increases RANKL expression in bone marrow stromal cells through CD44.Semantic proximity Read ↗

Identification of hyaluronic acid binding sites in the extracellular domain of CD44Semantic proximity Read ↗

CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.