Article
A Ser49Cys variant in the ataxia telangiectasia, mutated, gene that is more common in patients with breast carcinoma compared with population controls.
Cancer - 1 Apr 2004
Buchholz Thomas A, Weil Michael M, Ashorn Cheryl L, Strom Eric A, Sigurdson Alice, Bondy Melissa, Chakraborty Ranajit, Cox James D, McNeese Marsha D, Story Michael D
Abstract excerpt
BACKGROUND: Mothers of children who have ataxia telangiectasia have been reported to be at increased risk for development of breast carcinoma. To test whether sequence variants in the ataxia telangiectasia, mutated, gene (ATM) are associated with breast carcinoma, the authors compared the frequency of ATM cDNA sequence changes in patients with breast carcinoma with the corresponding frequency in control patients....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.