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Article

Variance-stabilizing transformations for two-color microarrays.

Bioinformatics (Oxford, England) - 22 Mar 2004

Durbin Blythe P, Rocke David M

Abstract excerpt

MOTIVATION: Authors of several recent papers have independently introduced a family of transformations (the generalized-log family), which stabilizes the variance of microarray data up to the first order. However, for data from two-color arrays, tests for differential expression may require that the variance of the difference of transformed observations be constant, rather than that of the transformed...

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PMID: 15033873
DOI: 10.1093/bioinformatics/btg464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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