Article
Global HIV-1 molecular epidemiology with special reference to genetic analysis of HIV-1 subtypes circulating in North India: functional and pathogenic implications of genetic variation.
Indian journal of experimental biology - 1 Jun 2009
Neogi Ujjwal, Sood Vikas, Banerjee Snigdha, Ghosh Nilanjana, Verma Sachin, Samrat Subodh, Sharma Yogeshwar, Saxena Abhishek, Husain Sajid, Ramachandran V G, Das S, Sreedhar K Vijesh, Goel Nidhi, Wanchu Ajay, Banerjea Akhil C
Abstract excerpt
HIV-1 displays extensive genetic diversity globally which poses challenge in designing a suitable antigen/immunogen to provoke desired protective immune response in host. HIV-1 mediated pathogenesis is complex and involves host genes, virus genes and other factors. A number of genetic subtypes have been identified based on sequence variations, largely in envelope region. Different genetic subtypes display...
Topics
- APOBEC-3G Deaminase
- Cytidine Deaminase
- Genetic Variation
- HIV Infections
- HIV Long Terminal Repeat
- HIV-1
- Human Immunodeficiency Virus Proteins
- Humans
- India